Here are 10 actors who played their best when acting opposite genders.
Cillian Murphy in Breakfast On Pluto
Angelina Jolie in Salt
Johnny Depp in Before Night Falls
Eddie Redmayne in The Danish Girl
Cate Blanchett in I’m Not There
Tilda Swinton in Suspiria
Jared Leto in Dallas Buyers Club
John Travolta in Hairspray
Robin Williams in Mrs. Doubtfire
Glenn Close in Hook
